J Vis Exp2025Featured
Cell Subtype-specific Analysis of Neuronal Membrane Proteasome in Somatosensory Neurons
Imhoff ME, Morris HJ, Villalón Landeros E (lab principal investigator)
Publications
Publications
Our peer-reviewed work on the neuronal membrane proteasome, pain signalling, and neurodegenerative disease.
29 publications
20252
- STAR Protocols2025Featured
Protocol to study neuronal membrane proteasome function in mouse peripheral sensory neurons
Krueger ER, Church TR, Brennan A, Türker F, Villalón Landeros E (lab principal investigator)
20241
- Cell Reports2024Featured
The nociceptive activity of peripheral sensory neurons is modulated by the neuronal membrane proteasome
Villalón Landeros E (lab principal investigator), Kho SC, Church TR, Brennan A, Türker F, Delannoy M, Caterina MJ, Margolis SS
20231
- American Journal of Physiology-Cell Physiology2023
Normal muscle fiber type distribution is recapitulated in aged ephrin-A3 −/− mice that previously lacked most slow myofibers
Arpke R, Moritz T, Hahn K, Stark D, Villalón E (lab principal investigator), Lorson C, Cornelison D
20223
- Human Molecular Genetics2022
Motor unit recovery following Smn restoration in mouse models of spinal muscular atrophy
Comley LH, Kline RA, Thomson AK, Woschitz V, Landeros EV (lab principal investigator), Osman EY, Lorson CL, Murray LM
- Human Molecular Genetics2022
A combinatorial approach increases SMN level in SMA model mice
Dumas SA, Villalón E (lab principal investigator), Bergman EM, Wilson KJ, Marugan JJ, Lorson CL, Burnett BG
- Human Molecular Genetics2022
The Ighmbp2D564N mouse model is the first SMARD1 model to demonstrate respiratory defects
Smith CE, Lorson MA, Ricardez Hernandez SM, Al Rawi Z, Mao J, Marquez J, Villalón E (lab principal investigator), Keilholz AN, Smith CL, Garro-Kacher MO, Morcos T, Davis DJ, Bryda EC, Nichols NL, Lorson CL
20212
- Molecular Therapy Methods & Clinical Development2021
Defining the optimal dose and therapeutic window in SMA with respiratory distress type I model mice, FVB/NJ-Ighmpb2 (nmd-2J)
Shababi M, Smith CE, Ricardez Hernandez SM, Marquez J, Al Rawi Z, Villalón E (lab principal investigator), Farris KD, Garro-Kacher MO, Lorson CL
- Journal of Cachexia, Sarcopenia and Muscle2021
Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression
McCormack NM, Villalón E (lab principal investigator), Viollet C, Soltis AR, Dalgard CL, Lorson CL, Burnett BG
20202
- Biochemical and Biophysical Research Communications2020
AAV9-DOK7 gene therapy reduces disease severity in Smn(2B/-) SMA model mice
Kaifer KA, Villalón E (lab principal investigator), Smith CE, Simon ME, Marquez J, Hopkins AE, Morcos TI, Lorson CL
- GeroScience2020
Lumbar spinal cord microglia exhibited increased activation in aging dogs compared with young adult dogs
Toedebusch CM, Garcia VB, Snyder JC, Jones MR, Schulz DJ, Johnson GC, Villalón E (lab principal investigator), Coates JR, Garcia ML
20195
- Human Molecular Genetics2019
AAV9-Stathmin1 gene delivery improves disease phenotype in an intermediate mouse model of spinal muscular atrophy
Villalón E (lab principal investigator), Kline RA, Smith CE, Lorson ZC, Osman EY, O’Day S, Murray LM, Lorson CL
- Biochemical and Biophysical Research Communications2019
Development of a novel severe mouse model of spinal muscular atrophy with respiratory distress type 1: FVB-nmd
Shababi M, Smith CE, Kacher M, Alrawi Z, Villalón E (lab principal investigator), Davis D, Bryda EC, Lorson CL
- Human Molecular Genetics2019
AAV9-mediated delivery of miR-23a reduces disease severity in Smn2B/-SMA model mice
Kaifer KA, Villalón E (lab principal investigator), O’Brien BS, Sison SL, Smith CE, Simon ME, Marquez J, O’Day S, Hopkins AE, Neff R, Rindt H, Ebert AD, Lorson CL
- Scientific Reports2019
Functional characterization of SMN evolution in mouse models of SMA
Osman EY, Bolding MR, Villalón E (lab principal investigator), Kaifer KA, Lorson ZC, Tisdale S, Hao Y, Conant GC, Pires JC, Pellizzoni L, Lorson CL
- Biochemical and Biophysical Research Communications2019
Muscle fiber-type selective propensity to pathology in the nmd mouse model of SMARD1
Villalón E (lab principal investigator), Lee NN, Marquez J, Lorson CL
20184
- Molecular Therapy Methods & Clinical Development2018
A Direct Comparison of IV and ICV Delivery Methods for Gene Replacement Therapy in a Mouse Model of SMARD1
Shababi M, Villalón E (lab principal investigator), Kaifer KA, DeMarco V, Lorson CL
- Experimental Neurology2018
Internode length is reduced during myelination and remyelination by neurofilament medium phosphorylation in motor axons
Villalón E (lab principal investigator), Barry DM, Byers N, Frizzi K, Jones MR, Landayan DS, Dale JM, Downer NL, Calcutt NA, Garcia ML
- Molecular and Cellular Neuroscience2018
Arginase-1 expressing microglia in close proximity to motor neurons were increased early in disease progression in canine degenerative myelopathy, a model of amyotrophic lateral sclerosis
Toedebusch CM, Snyder JC, Jones MR, Garcia VB, Johnson GC, Villalón EL (lab principal investigator), Coates JR, Garcia ML
- Human Molecular Genetics2018
Selective vulnerability in neuronal populations in nmd/SMARD1 mice
Villalón E (lab principal investigator), Shababi M, Kline R, Lorson ZC, Florea KM, Lorson CL
20174
- Human Molecular Genetics2017
Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy
Sison SL, Patitucci TN, Seminary ER, Villalon E (lab principal investigator), Lorson CL, Ebert AD
- Muscle & Nerve2017
Differential effects of myostatin deficiency on motor and sensory axons
Jones MR, Villalón E (lab principal investigator), Northcutt AJ, Calcutt NA, Garcia ML
- JCI Insight2017
Plastin-3 extends survival and reduces severity in mouse models of spinal muscular atrophy
Kaifer KA, Villalón E (lab principal investigator), Osman EY, Glascock JJ, Arnold LL, Cornelison DDW, Lorson CL
- Genes, Brain and Behavior2017
Muscle spindle alterations precede onset of sensorimotor deficits in Charcot-Marie-Tooth type 2E
Villalón E (lab principal investigator), Jones MR, Sibigtroth C, Zino SJ, Dale JM, Landayan DS, Shen H, Cornelison DD, Garcia ML
20162
- Molecular Therapy2016
Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent
Shababi M, Feng Z, Villalon E (lab principal investigator), Sibigtroth CM, Osman EY, Miller MR, Williams-Simon PA, Lombardi A, Sass TH, Atkinson AK, Garcia ML, Ko CP, Lorson CL
- Methods in Enzymology2016
Genetic Manipulation of Neurofilament Protein Phosphorylation
Jones MR, Villalón E (lab principal investigator), Garcia ML
20151
- Brain Research2015
Exacerbation of Charcot-Marie-Tooth type 2E neuropathy following traumatic nerve injury
Villalón E (lab principal investigator), Dale JM, Jones M, Shen H, Garcia ML
20141
- Methods in Molecular Biology2014
Real-time PCR quantification of gene expression in embryonic mouse tissue
Villalon E (lab principal investigator), Schulz DJ, Waters ST
20121
- Genes, Brain and Behavior2012
Expressing hNF-LE397K results in abnormal gaiting in a transgenic model of CMT2E
Dale JM, Villalon E (lab principal investigator), Shannon SG, Barry DM, Markey RM, Garcia VB, Garcia ML
For the complete and continuously updated record, see PubMed (opens in a new tab).